Thelper(Th)cellsplayanimportantroleinregulatingimmuneresponses.Theysecretecytokinestostimulatevariouseffectorcells,suchascytotoxicTcells,Bcells,andmacrophages.AccuratemeasurementofThcytokineexpressioniscriticaltoidentifythecorrespondingThcellsandforin-depthunderstandingoftheimmuneresponses.

TheHumanThCytokinePanelisamultiplexbead-basedassaypanel,usingfluorescence-encodedbeadssuitableforuseonvariousflowcytometers.Thispanelallowssimultaneousquantificationofthirteenhumancytokines,includingIL-2,IL-4,IL-5,IL-6,IL-9,IL-10,IL-13,IL-17A,IL-17F,IL-21,IL-22,IFN-γandTNF-α,whicharecollectivelysecretedbyTh1,Th2,Th9,Th17,Th22andTfollicularcells.ThisassaypanelprovideshigherdetectionsensitivitiesandbroaderdynamicrangesthantrADItionalELISAmethods.Thepanelhasbeenvalidatedforusewithserumandcellculturesupernatantsamples.Usecautionwhenusingplasmasamplesduetocompromisedaccuracyinthesesamples.

LEGENDplex™predefinedsubpanelsspecifictodifferentThelpersubsetsarealsoavailable.Inaddition,aMixandMatchsystemisavailabletocustomizeassaysforspecificitieswithinthisThcytokinepanel.